Abstract:
<p align="justify"> N-benzylidene-2-(4-chloro-3-methylphenoxy)acetohydrazides (3a-e), obtained by arylation of 2-(4-chloro-3-methyl phenoxy)acetohydrazide (2), was cyclized with acetic anhydride to yield 1-(5-(( 4-chloro-3-methylphenoxy)methyl)-2-phenyl-l ,3,4-oxadiazol- 3(2H)-yl)ethanones (4a-e). All the newly synthesized compounds were analytically and spectrally characterized and evaluated for anti-bacterial and anti-fungal activities. </p>