CHROMIUM (III) COMPLEX ANIONS IN THE CHEMICAL ANALYSIS. THIORIDAZINE DETERMINATION
Abstract:
<p align="justify"> Complex anions of Cr(III) analogues of Reinecke s salt, [Cr(NCS)<sub>4</sub>(amine)<sub>2</sub>] are good analytical reagents with high sensibility and selectivity for N-organic bases of pharmaceutical importance. We have observed that the phenothiazinic type drug, thioridazine, prescribed for the treatment of maniac-depressing psychosis precipitates with Cr(/11) complex anions. Some new oxidative methods for the determination of thioridazine (10-[2-(1-methyl-2-piperidinyl)ethyl]-2-(methylthio)-10H-phenothiazine) are described The results were evaluated statistically </p>
<p align="justify"> Complex anions of Cr(III) analogues of Reinecke s salt, [Cr(NCS)<sub>4</sub>(amine)<sub>2</sub>] are good analytical reagents with high sensibility and selectivity for N-organic bases of pharmaceutical importance. We have observed that the phenothiazinic type drug, thioridazine, prescribed for the treatment of maniac-depressing psychosis precipitates with Cr(/11) complex anions. Some new oxidative methods for the determination of thioridazine (10-[2-(1-methyl-2-piperidinyl)ethyl]-2-(methylthio)-10H-phenothiazine) are described The results were evaluated statistically </p>
DOI: 10.48141/SBJCHEM.v9.n10.2001.34_2001.pdf
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