THE ROLE OF EDUCATION IN FOSTERING ENTREPRENEURSHIP AND INNOVATION: INSIGHTS FROM DR. BHAVNA AMBUDKAR
Background: Dr. Bhavna, an experienced leader in education and innovation, has held various leadership positions, including head of department, dean of alumni relations, and president of the institutions innovation council. She has been instrumental in initiating the alumni cell at her previous organization and establishing world-class state-of-the-art laboratories in collaboration with the automotive sector. Aims: Dr. Bhavna's efforts aim to create an ecosystem for innovation and entrepreneurship within the institute and beyond, encouraging learners to consider entrepreneurship as a career option and fostering innovation in the electronics manufacturing domain. Methods: Dr. Bhavna's approach involves raising awareness about innovation and entrepreneurship among learners, fostering collaborations between academia and industry, and establishing world-class state-of-the-art laboratories to bridge the gap between academia and industry. Results: Dr. Bhavna's efforts have resulted in a strong alumni network, with graduates across the globe contributing to various domains and positions. She has also established world-class laboratories in collaboration with the automotive sector, fostering innovation and startups in the electronics manufacturing domain. Discussions: The Ministry of Electronics and Information Technology plays a significant role in initiating innovations and startups in the electronics manufacturing domain. They have generated a separate vertical for startups, which poses challenges to innovators. If a solution is validated, the ministry handholds the innovators, incubates their ideas, funds them, and helps them reach the market at the national and international levels. Conclusions: Dr. Bhavna's vision and efforts toward fostering an ecosystem for innovation and entrepreneurship within the institute and beyond are commendable. Her experience and achievements in various leadership roles, including as the head of the department and president of the institutions innovation council, have added significant value to her professional and personal life.
Read ArticleASSESSMENT OF SERUM SCLEROSTIN LEVEL AS A BIOMARKER ASSOCIATED WITH BONE DISORDERS IN Β-THALASSEMIA PATIENTS IN AL- NAJAF CITY, IRAQ
Background: β-thalassemia is a blood disorder in which the body does not make hemoglobin normally. Aim: To assess serum sclerostin in female patients with beta-thalassemia and compare with the healthy controls and to predict its complication associated with the bone pathophysiology, for designed improvement the lifestyle goodliness for these patients. Material and methods: Sixty-nine female beta-thalassemia (βT) patients (54 βT major and 15 βT Intermedia), aged 8-40 years who dependent on transfused blood, and 20 healthy controls were evaluated serum sclerostin, and was examined the relationship with hematological parameters RBC, Hb, PCV, WBC, PLT, BMI, splenic status, iron, and ferritin levels. The information of beta-thalassemia patients was collected and records by the questioner. Results: A significantly increased serum sclerostin level (mean 26.80±0.91) pg/ml was showed in βT patients compared with the healthy controls (10.03±0.68, p smaller than 0.001) pg/ml. Furthermore, a significant decrease (p smaller than 0.05) of the sclerostin level was observed in β-thalassemia major compared to intermedia β-thalassemia patients. Serum sclerostin level revealed a significant increase in progress age; it is highest in the age group (30-40) year as compared with age group (8-18) and (19-29) year respectively. Sclerostin showed no associations with the RBC, Hb, PCV, and significantly positively correlated (p smaller than 0.05) with serum iron, ferritin levels, WBC, and PLT count. Significantly higher sclerostin levels in splenectomized and underweight groups were observed compared to unsplenectomized and normal-weight groups (p smaller than 0.05) of βT patients. Conclusions: Sclerostin plays an important role in beta-thalassemia patients and can serve as a biomarker associated with the bone pathophysiology and indicator to prevent the continuation of such serious diseases caused by iron overload in these patients.
Read ArticleANALYTICAL METHODS FOR METHANOL DETECTION IN ALCOHOLIC BEVERAGES: A COMPARATIVE REVIEW OF CLASSICAL, COLORIMETRIC, AND CHROMATOGRAPHIC APPROACHES
Introduction: The detection of methanol in alcoholic beverages represents a critical public health issue, particularly in light of the recent outbreak of poisonings in Brazil, which registered 58 confirmed cases and 15 deaths through October 2025. Methanol's toxicity, with an estimated lethal dose ranging from 0.5 to 1.5 g/kg, requires reliable analytical methods for health surveillance. Brazilian legislation establishes a maximum limit of 20 mg/100 mL of anhydrous alcohol; however, the need for accessible screening methods in field settings remains an important challenge. Objective: To critically compare three analytical methods for methanol determination: classical qualitative methods (Lucas Test and dichromate/Schiff), Brazilian colorimetric method, and gas chromatography with flame ionization detector (GC-FID), evaluating their performance and applicability in resource-limited contexts. Methods: Theoretical-comparative approach through critical analysis of specialized literature and normative technical documentation. Methods were evaluated according to: operational principle, sensitivity (LOD/LOQ), selectivity, operational complexity, analysis time, and practical applicability. Results: The Lucas Test is not applicable for methanol detection. Colorimetric methods showed moderate sensitivity (LOD ~20-160 mg/100 mL), a 10-30-minute execution time, low operational complexity, and excellent portability. The Brazilian method presented chemical equivalence with international standards, differing only in the type of reading performed. GC-FID has shown superior sensitivity (LOD ≤ 1 mg/100 mL) and high specificity, but it requires extended time (~45-60 minutes), complex laboratory infrastructure, and specialized operators. Sugars interfere with colorimetric methods. Conclusions: The methods are complementary within a hierarchical system. Colorimetric methods enable rapid field screening, while GC-FID serves as the confirmatory method for forensic analyses. We recommend implementing integrated protocols that combine in situ colorimetric screening with GC-FID confirmation in accredited laboratories for effective health surveillance.
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