CONTENT OF ANTIOXIDANTS IN SOME MEDICINAL PLANTS SOLD IN GEORGIAN PHARMACY CHAINS
Background: Antioxidant compounds are widely used in medicine to protect the organism from the impact of various stresses and strengthen the immune system. The primary source of natural antioxidants is considered plant-based products. That is precisely why scientists are interested in extracting active compounds out of plant materials and use them. However, diverse resources of medicinal plants of Georgia is poorly studied and used as a source of antioxidants. Aim: The research aimed to study the antioxidant composition and total antioxidant activity of some dried medicinal plants sold in the pharmacy network in Tbilisi, Georgia. Methods: Several types of medicinal plants (3 berry plants and 3 herbaceous plants) sold in the pharmacy chain were chosen as the research object. These are Crataegus sp., Sorbus sp., Viburnum sp., Helichrysum sp., Leonurus quinquelobatus Gilib, Origanum vulgare L. Results: As a result, it has been found that the content of ascorbic acid and carotene in the studied plants is not so high to fill the daily intake of a man with an infusion prepared from one tablespoon. As for proline and the number of total antioxidants, all the plants we have chosen are high in content, considerably increasing their medicinal value. Discussion: The low amount of ascorbic acid and carotine found in studied plant, this increases their medicinal value, and in combination with other antioxidants/plants, the healing effect of the raw materials has been used. Conclusions: The studied plants are characterized by high levels of proline and antioxidant activity, so their infusions can be safely used as a source of antioxidants both in folk medicine and for the preparation of biologically active preparations.
Read ArticleEXTRACTION AND CHARACTERIZATION OF CURCUMIN FROM TURMERIC RHIZOMES GROWN IN MÉRIDA, VENEZUELA
The extraction of naturally occurring compounds is one of the fastest-growing industries because of its benefits against its synthetic analogs. Environmental protection must require the use of natural products instead of chemicals to minimize pollution. Thus, this investigation studies the use of some natural product, as curcumin, as naturally occurring acid‐base indicators. Curcumin can be used as acid-base indicators since it was found that it possesses pH-dependent solubility. Curcumin, the major active component of turmeric, Curcuma longa (Zingiberaceae), is used as a spice in curry and as a coloring agent in yellow mustards, cosmetics, pharmaceuticals, and hair dyes. In this research, the main compound colored rhizome of turmeric (Curcuma longa) cultivated in Mérida, Venezuela, is extracted: Curcumin (C21H20O6) (1E,6E)-1,7-bis(4-hydroxy-3-methoxyphenyl)-1,6-heptadiene-3,5-dione, in a yield of 3.42% after 8 hours of extraction using soxhlet extractor system with organic solvents (hexane and ethanol). The thin-layer chromatography and column performed separation and purification using a mobile phase, a mixture of chloroform-hexane 3:2. The dye was characterized by spectroscopic analysis of visible ultraviolet (UV-Vis) and infrared (IR), in addition to his studio in steering sensitivity as an acid-base indicator. This dye is useful as an acid-base indicator in strong acid-strong base volumes and did not require large amounts of it as it has high sensitivity. The results indicate that curcumin as an acid-base indicator allows the development of new standards in different chemistry fields that require this type of analysis.
Read ArticleCALCULATION FOR REDEMPTION OF COMPACT TESTING BY THE PROCTOR METHOD THROUGH NEWTON’S GRAVITATIONAL POTENTIAL ENERGY
Throughout this article, a study on the characteristics of the compaction test by the Proctor Method, regulated by ABNT NBR-7182, which is used to verify the degree of soil compaction, will be approached in order to broaden the discussion and raise points that demonstrate the urgent need to make it more accurate, efficient and safe. Through qualitative and quantitative research carried out by the authors of this article, it sought to collect data through a questionnaire for professionals in the field of geotechnics in the “Quadrilátero Ferrífero” region in Minas Gerais. In addition to other relevant data for the topic, it was raised that of the 22 professionals from the participating region, 72.7% of the total belief that the manual compaction test can be manipulated by an operator during the test execution, failing to generate results reliable, thus showing the importance of the proposed theme. In this way, we initially sought to correlate the Compaction Energy formula idealized by Ralph Proctor with Isaac Newton’s Gravitational Potential Energy formula and, through it, present the resizing, which may enable the construction of manual, semi-automatic human propulsion machines (not or making the automated ones that depend on electricity available to the market. In conclusion, from the mathematical calculations, it was possible to evidence the use of Newton’s Gravitational Potential Energy to constructnew equipment to carry out this test.
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