Latest Edition Highlights (Issue 41)

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CARDIOVASCULAR RISK AND DIETARY HABITS IN TRANSGENDER ADULTS RECEIVING HORMONE THERAPY

Background: Transgender and gender-diverse individuals experience health inequities that may increase cardiometabolic risk. Gender-affirming hormone therapy has been associated with changes in body composition, lipid metabolism, and cardiovascular risk markers. However, limited evidence is available regarding dietary habits and cardiovascular risk profiles in transgender populations in Latin America. Objective: To evaluate cardiovascular risk factors and cardioprotective food consumption among transgender adults receiving gender-affirming hormone therapy. Methods: A quantitative, observational, descriptive, and cross-sectional study was conducted in transgender adults undergoing gender-affirming hormone therapy in Mendoza, Argentina. Eighty-seven participants completed surveys regarding sociodemographic characteristics, lifestyle habits, nutritional counseling, and consumption of cardioprotective foods. We assessed anthropometric indicators and biochemical parameters related to cardiovascular risk. Statistical analyses were performed using GraphPad Prism 8. Data were analyzed using Spearman correlation, the chi-square test, and the Mann-Whitney U test. Results: A high prevalence of modifiable cardiovascular risk factors was identified, including overweight, sedentary behavior, smoking, and low intake of cardioprotective foods. More than half of the participants had never received nutritional counseling. No statistically significant differences were observed between transgender women and transgender men in the evaluated anthropometric and biochemical variables. Nevertheless, significant correlations were identified between body mass index, waist circumference, waist-to-height ratio, and atherogenic lipid markers. Dietary quality showed limited associations with cardiovascular risk indicators, although higher dietary quality was positively associated with HDL cholesterol levels in transgender men. Conclusion: The study highlights the presence of multiple cardiovascular risk factors in transgender individuals receiving gender-affirming hormone therapy and emphasizes the importance of integrating nutritional assessment and cardiometabolic monitoring into comprehensive transgender healthcare. These findings support the need for inclusive nutritional interventions and longitudinal studies addressing cardiovascular health in transgender populations.
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PHYSICOCHEMICAL AND PHYTOTOXIC QUALITY OF IRRIGATION WATER FOR THE TREES OF GENERAL SAN MARTÍN PARK, MENDOZA, ARGENTINA

Background: General San Martín Park, located in Mendoza, Argentina, is the city's most emblematic green infrastructure, designed in 1896 by architect Carlos Thays. The park plays a critical role in microclimate regulation, water conservation, and public health resilience. Aim: The purpose of this study was to assess the quality of the water used for irrigation in the most important park of the city of Mendoza, the General San Martín Park, through a comprehensive series of analyses. Methods: This study assessed the physicochemical and biological quality of irrigation water in the park, focusing on parameters such as temperature, pH, turbidity, electrical conductivity, hardness, alkalinity, nitrates, sulfates, and anthropogenic contaminants. Samples were collected at 20 points across the irrigation network during three periods (October 2024, April 2025, October 2025). Results: Indicate that irrigation water is generally of good quality, suitable for sustaining the park's forest mass. pH values remained within the optimal irrigation range (6.5–8.4), while nitrate levels were consistently below the 30 ppm threshold, with no nitrites detected. Hardness and alkalinity varied spatially, particularly near the Alto Godoy Water Treatment Plant, suggesting localized inputs of dissolved solids. Turbidity and conductivity strongly correlated with hardness, reflecting the influence of suspended and dissolved mineral content from runoff and seasonal hydrological dynamics of the Mendoza River. Importantly, we found no evidence of toxic anthropogenic contaminants such as heavy metals, cyanides, or petroleum derivatives. Discussion: Overall, the findings emphasize the need for continuous monitoring. From a management perspective. These results establish a baseline of water quality indicators for the park. They provide essential input for long-term strategies in conservation, recreation, and environmental education, ensuring resilience against water scarcity and urban expansion. The study underscores the park's role as both a cultural heritage site and a living laboratory for sustainable urban ecology.
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DIET, SUPPLEMENTATION, PERFORMANCE, AND SUBJECTIVE EXPERIENCE IN MARATHON RUNNERS

Background: Nutrition strategies may influence marathon performance and runners’ subjective experience. Aims: To evaluate the association between dietary habits, supplement use, performance, and subjective experience in runners of the 2025 Mendoza International Marathon. Methods: A survey of 240 runners from the 2025 Mendoza International Marathon examined dietary habits, supplement use, performance, and subjective experience. Results: Nutritional counseling was linked to more favorable perceptions. Conversely, pre-race alcohol and excessive carbohydrates with poor hydration increased gastrointestinal complaints. Supplements showed no measurable performance or well-being benefits. Discussions: These findings suggest that pre-race nutritional behaviors may have a greater influence on runners’ subjective experience than supplement use.Conclusions: Nutritional guidance may improve race experience, whereas poor pre-race practices increase gastrointestinal complaints.
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General information

SOUTHERN JOURNAL OF SCIENCES

    General information about this journal
  • Title: SOUTHERN JOURNAL OF SCIENCES
  • Short Title: South. J. Sci.
  • ISSN: 2764-5959 (Online); ISSN: 2764-5967 (Print)
  • Universal Decimal Classification (UDC): 001
  • Review Process: Double-Blind Peer-Review
  • Accessibility: Platinum Open Access, NO-APCs.
  • Digital preservation: Portico
  • Frequency of Publication: biannual [2 issues per year]. Journal publication schedule
  • DOI: 10.48141/2764-5959
  • Website: https://www.sjofsciences.com/
  • Country: BRAZIL
  • Publisher: Mendoza University - Argentina | Araucária - Scientific Association (leaving).
  • Language of Publication: ENGLISH / PORTUGUESE* / SPANISH**
  • *Year the Journal started accepting manuscripts in Portuguese: 2020
  • *Year the Journal started accepting manuscripts in Spanish: 2026
  • First issue year: 1993
  • Free full text: Yes
  • Indexed in: Index Copernicus; Latindex, and I2OR.
  • Formerly known as the Southern Brazilian Journal of Chemistry (1993 to 2021).
  • Former ISSN: 2674-6891 (Online); Former ISSN: 0104-5431 (Print).
  • Website last update: 18/09/2026.

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NATURAL EXTRACTS AS A PROMISING SOLUTION FOR GRAM-POSITIVE ANTIBIOTIC RESISTANCE: A COMPREHENSIVE REVIEW

Background: Antibiotic resistance is currently one of the biggest problems in public health. Infectious diseases are the second human death cause, and the emergence of antimicrobial-resistant bacteria increases mortality and morbidity rates. There is a growing clinical need for the development of new antibiotics. In this line, WHO issued an alert about 12 bacteria with an urgent need to develop new antibiotics. Aims: This review aims to analyze the current knowledge of their antibacterial activity against the gram-positive pathogens listed by WHO and their extraction techniques. Methods: We systematically reviewed the literature in PubMed, searching publications describing the use of natural extracts as antibiotics over bacteria. The exclusion criteria consisted of limiting papers on natural extracts tested over the bacteria culture related to eleven selected bacteria, according to an alert issued by WHO in 2017, and seven plant extracts. Results: All the gram-positive bacteria present in the WHO alert have been treated, with different degrees of advance, with some of the plant extracts and plant-based compounds reviewed. Currently, they are in the preclinical stage. Edible herbs are more often used, as well as artemisia and wine byproducts. Discussion: Natural products based on plants have shown to be efficient in inhibiting bacterial growth, even in antibiotic-resistant strains. The classical extraction methods are still in use and have been improved with the available technology to improve efficiency and yield. Conclusions: Ongoing evidence shows that plant extracts and plant-based compounds are effective as antibacterial, with minimal effects on the host cell, a promising antibiotic source. Furthermore, they are sustainable, environmentally friendly, and renewable.
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SELF-ASSEMBLED MULTILAYERS OF WATER GLUCOSE MODIFIED-CHITOSAN AND GLUCOSE OXIDASE FOR DETECTION OF GLUCOSE IN MILK SAMPLES

Background: A crucial aspect of electrochemical enzymatic biosensor development is the immobilization of the enzymes, as it directly influences the sensitivity of the bioelectrode. Among the different methods used to incorporate enzymes on the surface of the transducers, layer-by-layer (LbL) self-assembly based on electrostatic interaction with polyelectrolytes of opposite charge stands out due to its simplicity and reproducibility. Aims: The aim of the work was to develop an electrochemical glucose biosensor by LbL assembly of a new functionalized chitosan polycation and the enzyme glucose oxidase (GOx). Methods: Chitosan was chemically functionalized with glucose by the Maillard reaction. The resulting polycation, named G-Chit, is soluble in the medium compatible with the enzyme. The bioelectrode was obtained by alternating adsorption of G-Chit and GOx onto carbon paste electrodes. By selecting the number of bilayer of G-Chit/GOX, the enzyme concentration, and the pH, the electroanalytical performance of the biosensor was optimized. The electrochemical responses were characterized by cyclic voltammetry and chronoamperometry. Results: Under optimized experimental conditions, the biosensor exhibited a sensitivity of (0.81 ± 0.03) µA mM-1 in a glucose concentration range of (0.18 to 1.75) mM. Discussion: Results indicated that catalytic response increases both with the number of G-Chit/GOx bilayers and the enzyme concentration, obtaining the best responses for 3 bilayers and 2 mg mL-1, respectively, while the optimum working pH value was 7.0. Conclusions: The analytical response of the biosensor was tested in milk samples with negligible matrix effects, suggesting a potential application in other dairy products. Results show that G-Chit appears promising for the immobilization of enzymes.
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ASSESSMENT OF THE IRRIGATION WEIR REMOVAL IN THE ENGURI RIVER

Background: Dams are one of the biggest threats to aquatic biodiversity. They restrict the movement of migratory fish. The construction of barriers can cause the complete extinction of some species from the rivers. When a dam can no longer perform its function or research will determine the need to demolish it, dams are often removed. In the lower part of the Enguri River, Georgia, an irrigation weir is currently non-functional. Aims: This research aims to prove the need to demolish the dam construction on the 44th km of the Enguri River, as it negatively impacts biodiversity and creates an artificial barrier in the river. Methods: Visual inspection was used as a method to assess the morphology and habitat of the dam where it is located. The conversation method was used with Engurhesi LTD representatives to understand the current function of the dam. The Questions were related to the current function of the dam. Results: Based on the conservation with Engurhesi LTD representatives, the study has shown that there is no reason that an irrigation weir might be left in its current state on the Enguri River. Based on the studies, the damage to biodiversity is real and disturbing. Discussion: The irrigation weir on the Enguri River was left untended because of the construction of the Enguri dam. Currently, there is no reason to divert the river Enguri with the help of an irrigation weir as there is no excess water in this river. Conclusions: In conclusion, it can be said that it is necessary to remove the irrigation weir on the Enguri River to restore habitat and mitigate the threats to biodiversity.
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SOUTHERN JOURNAL OF SCIENCES

The SOUTHERN JOURNAL OF SCIENCES publishes articles in Chemistry, Physics, Mathematics, Biology, Pharmacy, Medicine, Engineering, Industrial Science, Agriculture, and related interdisciplinary areas and is intended to fill a gap in terms of scientific information worldwide. All manuscripts can be published either in English or Portuguese, with tile, abstracts, and keywords in English. At present, there are NO PUBLICATION FEES. Editors will cover web hosting, open access, DOI number, and other service costs.

We have set high standards for the articles to be published by ensuring strong but fair refereeing by at least two reviewers. We hope that this Journal will provide a forum for disseminating high-quality research in chemistry and related areas and are open to any questions and suggestions. Starting in 2020, the SOUTHERN JOURNAL OF SCIENCES will have two issues per year (June and December).

Thank you very much for choosing the SOUTHERN JOURNAL OF SCIENCES to publish your paper!
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