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INQUIRY FOR SUITABLE LOCATIONS FOR A DRILLING REGIME AT AN UPSLOPE ROCKY KNOLL OF LAWU ESTATE, WESTERN BYPASS, MINNA, NIGERIA

Background: A client requested that the study group help determine locations that would be suitable for a drilling regime at his lot, located at an upslope rocky knoll of Lawu Estate, Minna, Nigeria. Aim: The aim of this study is to carry out a purpose-specific survey to pinpoint the best locations in a built-up property at the upmarket Lawu Estate that would be suitable for a drilling regime targeted for household consumption. Methods: The study area was reconnoitered by the survey crew in order to georeference the locations that would be occupied for the vertical electrical sounding survey in the 30 m x 20 m lot. Owing to the extensive build-up at this lot, only a four-point traverse along the 30-metric dimension traverse of the frontage of the building was demarcated in the northeasterly direction, thereby limiting the desire of the survey crew to define an appropriate survey grid. The data-acquisition pattern at the 4 x 1 survey stations of the frontage-traverse of the lot followed the “traditional” sequence of Schlumberger array layout measurements, whence the survey crew progressed with current-electrode spacing either end of a survey point located at this frontage-traverse targeting a maximum survey depth of 100 m. Result: The acquired vertical electrical-sounding data set for this study was recorded on purpose-specific data sheets. Discussion: Based on empirical rules-of-thumb procedures for interpreting vertical electrical sounding data at the Nigerian Basement Complex geological province, “assured” groundwater location and “strongly aquiferous” location, deductive inferences were drawn with regards to only vertical electrical sounding Station 4. Conclusion: Thus, it is recommended that VES Station 4 be exploited in the planned drilling program of the client, especially since this survey point checks off 100 percent of the constraints imposed by the rules-of-thumb interpretation procedures.
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INTERVIEW WITH DEPUTY VICE CHANCELLOR DR. O. A. OMOTESHO, UNIVERSITY OF ILORIN, NIGERIA (ENGLISH VERSION)

Background: The University of Ilorin, founded in 1975 in Nigeria, has evolved from 3 to 16 faculties, becoming the country's most sought-after institution for the past two decades. Aims: To document the institutional evolution, identify the most demanded programs, assess scientific output, examine internationalization strategies, and understand strategic development objectives. Methods: Structured interview with Vice-Chancellor Dr. Olubumi Abayomi Omotesho, following a standardized protocol covering historical, academic, scientific, and strategic aspects of the institution, under Creative Commons license format. Results: The university expanded to 16 faculties in 49 years. The most demanded programs are Medicine and Nursing, followed by Pharmacy, Law, Engineering, and Accounting. Areas with the highest scientific output: Medicine, Biological/Agricultural Sciences, and Engineering. It offers 340 postgraduate programs with approximately 7,523 students. There is a dedicated infrastructure for internationalization, with plans for international accommodations. Discussion: The predominance of healthcare courses reflects global employability trends. Research aligned with Sustainable Development Goals demonstrates a contemporary vision. The institutional goal (number one in Nigeria, top 10 in Africa, top 500 globally) shows a measurable strategic approach. Commitment to internationalization aligns with global education trends. Conclusions: The institution exemplifies an evolving African university focused on academic excellence, scientific relevance, and internationalization. The prioritization of student-centered development, clear positioning goals, and international collaboration initiatives establish solid foundations for its contribution to regional and global knowledge.
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RESEARCH LANDSCAPE OF REPURPOSED MEDICATIONS IN CANCER TREATMENT: A MULTI-DATABASE BIBLIOMETRIC ANALYSIS OF ELEVEN OFF-PATENT THERAPEUTICS

Background: Drug repurposing offers potential advantages for cancer therapy development, particularly when utilizing medications with established safety profiles and expired patents. While individual repurposed medications have been investigated for oncological applications, comprehensive comparative analyses of research distribution patterns across multiple therapeutic candidates appear limited in the literature. Understanding these patterns may provide insights into research priorities and potential knowledge gaps. Aim: This exploratory study was designed to quantify and compare the volume of scientific literature examining the anticancer potential of eleven selected off-patent medications across different pharmacological classes. Methods: Bibliometric searches were conducted across five databases (Google Scholar, BVS, PubMed, NIH, and Science.gov) using standardized search terms combining each medication name with "cancer" and "cancer treatment." The selected medications included ivermectin, fenbendazole, mebendazole, albendazole, metformin, propranolol, disulfiram, valproic acid, thalidomide, dexamethasone, and hydroxychloroquine. Basic statistical analyses were performed to examine the distribution patterns and correlations within the database. Results: The search yielded 3,226,066 total publications with considerable variation in distribution patterns. Dexamethasone accounted for the largest proportion (1,538,058 publications, 47.68%), followed by metformin (697,172 publications, 21.61%). Some medications with smaller overall publication volumes demonstrated higher proportions of treatment-specific research, such as fenbendazole (87.82%), disulfiram with copper (86.54%), and hydroxychloroquine with zinc (75.21%). The Herfindahl Index indicated a high concentration of research attention (0.2870). Discussion: The findings suggest substantial variation in research attention across the selected medications. While some medications dominate the literature, others with focused treatment-specific research may warrant further investigation. The inverse relationship observed between total publication volume and treatment specificity suggests that research patterns in this field may be more complex than absolute publication counts indicate. Conclusions: This preliminary bibliometric assessment reveals an uneven distribution of research attention among repurposed medications being investigated for cancer applications. These patterns may inform future research prioritization, though further qualitative analysis would be valuable to assess the clinical significance of these quantitative observations.
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General information

SOUTHERN JOURNAL OF SCIENCES

    General information about this journal
  • Title: SOUTHERN JOURNAL OF SCIENCES
  • Short Title: South. J. Sci.
  • ISSN: 2764-5959 (Online); ISSN: 2764-5967 (Print)
  • Universal Decimal Classification (UDC): 001
  • Review Process: Double-Blind Peer-Review
  • Accessibility: Platinum Open Access, NO-APCs.
  • Digital preservation: Portico
  • Frequency of Publication: biannual [2 issues per year]. Journal publication schedule
  • DOI: 10.48141/2764-5959
  • Website: https://www.sjofsciences.com/
  • Country: BRAZIL
  • Publisher: Araucária - Scientific Association.
  • Language of Publication: ENGLISH / PORTUGUESE*
  • *Year that the Journal started accepting manuscripts in Portuguese: 2020
  • First issue year: 1993
  • Free full text: Yes
  • Indexed in: Index Copernicus; Latindex, and I2OR.
  • Formerly known as the Southern Brazilian Journal of Chemistry (1993 to 2021).
  • Former ISSN: 2674-6891 (Online); Former ISSN: 0104-5431 (Print).
  • Website last update: 06/07/2025.

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MANAGEMENT MODEL FOR CONSTRUCTION WASTE PRODUCED IN THE CITY OF RIO DE JANEIRO

Background: A new management model for construction and demolition waste (CDW) was proposed for the city of Rio de Janeiro, hence waste the city planning area estimated generation; the results were compared with the data published by COMLURB and SNIS through the statistics tests was proved that CDW had been dispersed, which support the hypothesis that the current model cause dispersion of the rubble. Aim: This study proposes a new management model for CDW to the city, according to regions where occur the higher production of rubble. Methods: The estimation of rubble was obtained through the issued licenses from 2006 to 2020 published by SMPU. The quantification of rubble in the city was carried out by adopting the generation indicator from licensed construction activities. The amount of CDW published by COMLURB and SNIS was compared through statistics tests ANOVA and T-Test, the second period from 2006 to 2020 and 2011 to 2020. To measure the area to implant a CDW recycling plant, criteria from production capacity were used. Results: ANOVA test to data from 2006 to 2020 and 2011 to 2020, according to a confidence interval of 95%, found the P value 0.589 and 0.022, respectively, it was verified that the significant difference is between data from COMLURB and Estimated. The T-test was applied from the same period in data from SNIS and estimated the P values 0.399 and 0.014. Discussion: The data from Estimating between 2006 and 2020 showed the best representation. The Área de Planejamento – AP (Planning Area) 4 was where 50.70% of the total rubble, after the AP 3 with 17.66%, the AP 5 was estimated at 16.59%, last of all, AP 2 and AP 1 were calculated the generation of 8.28% and 6.77%, respectively. Therefore, sizing the CDW recycling producing 361,99.00 tons per year demands an area of 32,397.50 m². Conclusions: It was concluded that the receipt of CDW in transfer stations managed by COMLURB is not allowed; therefore, the need to create a construction waste recycling plant was presented, to this end, it is necessary to have an available area of approximately 32,397.50 m².
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THE ROLE OF EDUCATION IN FOSTERING ENTREPRENEURSHIP AND INNOVATION: INSIGHTS FROM DR. BHAVNA AMBUDKAR

Background: Dr. Bhavna, an experienced leader in education and innovation, has held various leadership positions, including head of department, dean of alumni relations, and president of the institutions innovation council. She has been instrumental in initiating the alumni cell at her previous organization and establishing world-class state-of-the-art laboratories in collaboration with the automotive sector. Aims: Dr. Bhavna's efforts aim to create an ecosystem for innovation and entrepreneurship within the institute and beyond, encouraging learners to consider entrepreneurship as a career option and fostering innovation in the electronics manufacturing domain. Methods: Dr. Bhavna's approach involves raising awareness about innovation and entrepreneurship among learners, fostering collaborations between academia and industry, and establishing world-class state-of-the-art laboratories to bridge the gap between academia and industry. Results: Dr. Bhavna's efforts have resulted in a strong alumni network, with graduates across the globe contributing to various domains and positions. She has also established world-class laboratories in collaboration with the automotive sector, fostering innovation and startups in the electronics manufacturing domain. Discussions: The Ministry of Electronics and Information Technology plays a significant role in initiating innovations and startups in the electronics manufacturing domain. They have generated a separate vertical for startups, which poses challenges to innovators. If a solution is validated, the ministry handholds the innovators, incubates their ideas, funds them, and helps them reach the market at the national and international levels. Conclusions: Dr. Bhavna's vision and efforts toward fostering an ecosystem for innovation and entrepreneurship within the institute and beyond are commendable. Her experience and achievements in various leadership roles, including as the head of the department and president of the institutions innovation council, have added significant value to her professional and personal life.
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INVESTIGATING THE EFFECT OF COLD TEMPERATURE STRESS ON UNOPENED MALE CATKINS AND INOCULATED FEMALE FLOWERS OF IRANIAN NATIVE HAZELNUT CULTIVARS

In many low-temperature areas, the environmental factor is an important limiting factor for the production and distribution of horticultural plants. This study aimed to investigate the cold tolerance of the male catkins and inoculated female flowers to screen the popular native hazelnut cultivars in Qazvin under low-temperature stress. A completely randomized factorial block design with three replications was used in this experiment with eight cultivars (Nakhnroud, Khandan, Mish-Pestan, South of Qarabagh, Asl-e-Qarabagh, Rasmi, and Gerdashkevar). After removing each of the treated samples at the end of the experiment, the samples were examined morphologically (appearance) and compared with the control. The changes were recorded as qualitative traits. To understand the influence of cold stress on reproductive organs, hydrogen peroxide and proline were measured. The results showed the onset of freezing in unopened male catkins at -7 and -9 °C and in inoculated female flowers at -3 °C. Damage to unopened male catkins' tissue occurred at -11 °C and in female flowers at -5 °C. The highest value observed among cultivars in the case for proline content of male catkins was in Mish-Pestan and Khandan cultivars with 0.816 and 0.660 µmol/ g FW, respectively. In inoculated female flowers, Mish-Pestan and Tabestaneh cultivars with 0.185 and 0.168 µmol/ g FW, respectively, showed the highest statistically significantincrease in proline content. Interestingly, the cultivars with the highest proline content in male catkins indicated the most increase in H2O2; Mish-Pestan and Khnadan with 0.569 and 0.541 ug/g FW, respectively. Asl-eQarabagh was observed to have the least H2O2 content (0.042 ug/g FW) among cultivars. Again, in inoculated female flowers, those with the highest concentration of proline (Mish-Pestan and Tabestaneh) were found to have the highest H2O2 content (0.335 and 0.331 ug/g FW, respectively
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SOUTHERN JOURNAL OF SCIENCES

The SOUTHERN JOURNAL OF SCIENCES publishes articles in Chemistry, Physics, Mathematics, Biology, Pharmacy, Medicine, Engineering, Industrial Science, Agriculture, and related interdisciplinary areas and is intended to fill a gap in terms of scientific information worldwide. All manuscripts can be published either in English or Portuguese, with tile, abstracts, and keywords in English. At present, there are NO PUBLICATION FEES. Editors will cover web hosting, open access, DOI number, and other service costs.

We have set high standards for the articles to be published by ensuring strong but fair refereeing by at least two reviewers. We hope that this Journal will provide a forum for disseminating high-quality research in chemistry and related areas and are open to any questions and suggestions. Starting in 2020, the SOUTHERN JOURNAL OF SCIENCES will have two issues per year (June and December).

Thank you very much for choosing the SOUTHERN JOURNAL OF SCIENCES to publish your paper!
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