Latest Edition Highlights (Issue 39)

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INTERVIEW WITH DEPUTY VICE CHANCELLOR DR. O. A. OMOTESHO, UNIVERSITY OF ILORIN, NIGERIA (ENGLISH VERSION)

Background: The University of Ilorin, founded in 1975 in Nigeria, has evolved from 3 to 16 faculties, becoming the country's most sought-after institution for the past two decades. Aims: To document the institutional evolution, identify the most demanded programs, assess scientific output, examine internationalization strategies, and understand strategic development objectives. Methods: Structured interview with Vice-Chancellor Dr. Olubumi Abayomi Omotesho, following a standardized protocol covering historical, academic, scientific, and strategic aspects of the institution, under Creative Commons license format. Results: The university expanded to 16 faculties in 49 years. The most demanded programs are Medicine and Nursing, followed by Pharmacy, Law, Engineering, and Accounting. Areas with the highest scientific output: Medicine, Biological/Agricultural Sciences, and Engineering. It offers 340 postgraduate programs with approximately 7,523 students. There is a dedicated infrastructure for internationalization, with plans for international accommodations. Discussion: The predominance of healthcare courses reflects global employability trends. Research aligned with Sustainable Development Goals demonstrates a contemporary vision. The institutional goal (number one in Nigeria, top 10 in Africa, top 500 globally) shows a measurable strategic approach. Commitment to internationalization aligns with global education trends. Conclusions: The institution exemplifies an evolving African university focused on academic excellence, scientific relevance, and internationalization. The prioritization of student-centered development, clear positioning goals, and international collaboration initiatives establish solid foundations for its contribution to regional and global knowledge.
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THE REVOLUTION IN AMERICAN PUBLIC HEALTH POLICY: PETROLEUM-BASED DYES AND THE CHRONIC DISEASE EPIDEMIC

Background: The American food regulatory landscape has historically been influenced by industry interests, resulting in the widespread use of petroleum-derived synthetic food dyes banned in European countries. Chronic disease rates in American children have increased from 3% in the 1960s to approximately 60% currently, with annual healthcare costs reaching $1 trillion. The appointment of Robert F. Kennedy Jr. as Secretary of Health and Human Services marks a paradigmatic shift toward transparency and industry accountability in food safety regulation. Aim: This forum analysis examines Kennedy Jr.'s revolutionary approach to food safety regulation, particularly his confrontational stance against petroleum-based food additives exemplified by his statement, "if they want to eat petroleum, they should add it themselves at home" and evaluates the broader implications for American public health policy and global regulatory standards. Methods: Critical analysis of Kennedy Jr.'s public policy statements, examination of epidemiological data trends, and evaluation of proposed regulatory frameworks through content analysis of official speeches and policy declarations from the Department of Health and Human Services. Results: Kennedy Jr.'s administration targets the systematic elimination of synthetic food dyes through industry partnerships, scientific transparency initiatives, and restoration of rigorous research standards. His confrontational rhetorical approach, compared to Mike Tyson's boxing style, has generated unprecedented industry cooperation with food companies "calling almost daily" seeking compliance guidance. The strategy combines voluntary industry agreements with open-source information databases and enhanced FOIA access. Discussion: This confrontational rhetoric represents unprecedented directness in health policy communication, challenging decades of established regulatory practices. The approach prioritizes scientific transparency over diplomatic language, generating both media attention and voluntary industry engagement that traditional regulatory pressure failed to achieve. Conclusions: Kennedy Jr.'s revolutionary stance may establish new global standards for food additive oversight, prioritizing public health over commercial interests through evidence-based policymaking and industry accountability measures. This paradigm shift from reactive to preventive regulatory models could influence international food safety governance and restore American leadership in global health policy.
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RESEARCH LANDSCAPE OF REPURPOSED MEDICATIONS IN CANCER TREATMENT: A MULTI-DATABASE BIBLIOMETRIC ANALYSIS OF ELEVEN OFF-PATENT THERAPEUTICS

Background: Drug repurposing offers potential advantages for cancer therapy development, particularly when utilizing medications with established safety profiles and expired patents. While individual repurposed medications have been investigated for oncological applications, comprehensive comparative analyses of research distribution patterns across multiple therapeutic candidates appear limited in the literature. Understanding these patterns may provide insights into research priorities and potential knowledge gaps. Aim: This exploratory study was designed to quantify and compare the volume of scientific literature examining the anticancer potential of eleven selected off-patent medications across different pharmacological classes. Methods: Bibliometric searches were conducted across five databases (Google Scholar, BVS, PubMed, NIH, and Science.gov) using standardized search terms combining each medication name with "cancer" and "cancer treatment." The selected medications included ivermectin, fenbendazole, mebendazole, albendazole, metformin, propranolol, disulfiram, valproic acid, thalidomide, dexamethasone, and hydroxychloroquine. Basic statistical analyses were performed to examine the distribution patterns and correlations within the database. Results: The search yielded 3,226,066 total publications with considerable variation in distribution patterns. Dexamethasone accounted for the largest proportion (1,538,058 publications, 47.68%), followed by metformin (697,172 publications, 21.61%). Some medications with smaller overall publication volumes demonstrated higher proportions of treatment-specific research, such as fenbendazole (87.82%), disulfiram with copper (86.54%), and hydroxychloroquine with zinc (75.21%). The Herfindahl Index indicated a high concentration of research attention (0.2870). Discussion: The findings suggest substantial variation in research attention across the selected medications. While some medications dominate the literature, others with focused treatment-specific research may warrant further investigation. The inverse relationship observed between total publication volume and treatment specificity suggests that research patterns in this field may be more complex than absolute publication counts indicate. Conclusions: This preliminary bibliometric assessment reveals an uneven distribution of research attention among repurposed medications being investigated for cancer applications. These patterns may inform future research prioritization, though further qualitative analysis would be valuable to assess the clinical significance of these quantitative observations.
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General information

SOUTHERN JOURNAL OF SCIENCES

    General information about this journal
  • Title: SOUTHERN JOURNAL OF SCIENCES
  • Short Title: South. J. Sci.
  • ISSN: 2764-5959 (Online); ISSN: 2764-5967 (Print)
  • Universal Decimal Classification (UDC): 001
  • Review Process: Double-Blind Peer-Review
  • Accessibility: Platinum Open Access, NO-APCs.
  • Digital preservation: Portico
  • Frequency of Publication: biannual [2 issues per year]. Journal publication schedule
  • DOI: 10.48141/2764-5959
  • Website: https://www.sjofsciences.com/
  • Country: BRAZIL
  • Publisher: Araucária - Scientific Association.
  • Language of Publication: ENGLISH / PORTUGUESE*
  • *Year that the Journal started accepting manuscripts in Portuguese: 2020
  • First issue year: 1993
  • Free full text: Yes
  • Indexed in: Index Copernicus; Latindex, and I2OR.
  • Formerly known as the Southern Brazilian Journal of Chemistry (1993 to 2021).
  • Former ISSN: 2674-6891 (Online); Former ISSN: 0104-5431 (Print).
  • Website last update: 06/07/2025.

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INVESTIGATING THE EFFECT OF COLD TEMPERATURE STRESS ON UNOPENED MALE CATKINS AND INOCULATED FEMALE FLOWERS OF IRANIAN NATIVE HAZELNUT CULTIVARS

In many low-temperature areas, the environmental factor is an important limiting factor for the production and distribution of horticultural plants. This study aimed to investigate the cold tolerance of the male catkins and inoculated female flowers to screen the popular native hazelnut cultivars in Qazvin under low-temperature stress. A completely randomized factorial block design with three replications was used in this experiment with eight cultivars (Nakhnroud, Khandan, Mish-Pestan, South of Qarabagh, Asl-e-Qarabagh, Rasmi, and Gerdashkevar). After removing each of the treated samples at the end of the experiment, the samples were examined morphologically (appearance) and compared with the control. The changes were recorded as qualitative traits. To understand the influence of cold stress on reproductive organs, hydrogen peroxide and proline were measured. The results showed the onset of freezing in unopened male catkins at -7 and -9 °C and in inoculated female flowers at -3 °C. Damage to unopened male catkins' tissue occurred at -11 °C and in female flowers at -5 °C. The highest value observed among cultivars in the case for proline content of male catkins was in Mish-Pestan and Khandan cultivars with 0.816 and 0.660 µmol/ g FW, respectively. In inoculated female flowers, Mish-Pestan and Tabestaneh cultivars with 0.185 and 0.168 µmol/ g FW, respectively, showed the highest statistically significantincrease in proline content. Interestingly, the cultivars with the highest proline content in male catkins indicated the most increase in H2O2; Mish-Pestan and Khnadan with 0.569 and 0.541 ug/g FW, respectively. Asl-eQarabagh was observed to have the least H2O2 content (0.042 ug/g FW) among cultivars. Again, in inoculated female flowers, those with the highest concentration of proline (Mish-Pestan and Tabestaneh) were found to have the highest H2O2 content (0.335 and 0.331 ug/g FW, respectively
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THERMAL AND ECONOMIC ANALYSIS OF LIME PRODUCTION

The ore beneficiation process uses little technology, but mining companies have high economic performance. As an energy source, firewood plays a fundamental role due to its simple storage, low cost, great availability of forests, and lack of processing. Thus, the present work aims to analyze the consumption of firewood as fuel and possible improvements in the process for the production of lime in terms of harnessing raw materials and costs. Calcium oxide is obtained from the thermal decomposition of calcium and magnesium carbonates obtained from dolomitic deposits of limestone (CaCO3 : CaMgCO3). After CaO extraction, it is subjected to a calcination process, removing carbon dioxide (CO2) in ovens that work at temperatures between 900 and 1200°C. The source of energy applied to the calcination furnaces in the analyzed area is wood. The wood has a calorific value between 2,250 and 2,700 Kcal/Kg, but the moisture content responsible for the thermal variation must be considered. The firewood burning process was carried out in a ravine type oven where the temperature at which operators are exposed to heat was evaluated. The results indicated that the cooking time dropped by 20% as the amount of wood is fed into the oven. This increase represents a significant gain in lime production, thus leading to a higher profit for the company.  
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STUDY OF ALAZANI RIVER AND SURFACE WATER COMPOSITION IN SOME VILLAGES OF KAKHETI REGION OF GEORGIA

The article reviews the chemical composition of borehole and surface waters in three villages of one of the regions of Georgia - Kakheti, Gurjaani Municipality. The study was specifically focused on iodine content in waters. It turned out that certain amount of iodine really existed in borehole waters, which means that by everyday drinking of water, the human body gets maybe not the complete required amount of iodine, but at least some part of it. It was also discovered, that according to certain parameters, waters are clean, do not contain heavy metals and can be freely used for drinking and cooking. The chemical composition of the Alazani River was also examined according to all four seasons. This river is interesting because of being used for irrigation of vineyards and fruit gardens.
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SOUTHERN JOURNAL OF SCIENCES

The SOUTHERN JOURNAL OF SCIENCES publishes articles in Chemistry, Physics, Mathematics, Biology, Pharmacy, Medicine, Engineering, Industrial Science, Agriculture, and related interdisciplinary areas and is intended to fill a gap in terms of scientific information worldwide. All manuscripts can be published either in English or Portuguese, with tile, abstracts, and keywords in English. At present, there are NO PUBLICATION FEES. Editors will cover web hosting, open access, DOI number, and other service costs.

We have set high standards for the articles to be published by ensuring strong but fair refereeing by at least two reviewers. We hope that this Journal will provide a forum for disseminating high-quality research in chemistry and related areas and are open to any questions and suggestions. Starting in 2020, the SOUTHERN JOURNAL OF SCIENCES will have two issues per year (June and December).

Thank you very much for choosing the SOUTHERN JOURNAL OF SCIENCES to publish your paper!
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