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INTERVIEW WITH DEPUTY VICE CHANCELLOR DR. O. A. OMOTESHO, UNIVERSITY OF ILORIN, NIGERIA (ENGLISH VERSION)

Background: The University of Ilorin, founded in 1975 in Nigeria, has evolved from 3 to 16 faculties, becoming the country's most sought-after institution for the past two decades. Aims: To document the institutional evolution, identify the most demanded programs, assess scientific output, examine internationalization strategies, and understand strategic development objectives. Methods: Structured interview with Vice-Chancellor Dr. Olubumi Abayomi Omotesho, following a standardized protocol covering historical, academic, scientific, and strategic aspects of the institution, under Creative Commons license format. Results: The university expanded to 16 faculties in 49 years. The most demanded programs are Medicine and Nursing, followed by Pharmacy, Law, Engineering, and Accounting. Areas with the highest scientific output: Medicine, Biological/Agricultural Sciences, and Engineering. It offers 340 postgraduate programs with approximately 7,523 students. There is a dedicated infrastructure for internationalization, with plans for international accommodations. Discussion: The predominance of healthcare courses reflects global employability trends. Research aligned with Sustainable Development Goals demonstrates a contemporary vision. The institutional goal (number one in Nigeria, top 10 in Africa, top 500 globally) shows a measurable strategic approach. Commitment to internationalization aligns with global education trends. Conclusions: The institution exemplifies an evolving African university focused on academic excellence, scientific relevance, and internationalization. The prioritization of student-centered development, clear positioning goals, and international collaboration initiatives establish solid foundations for its contribution to regional and global knowledge.
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INQUIRY FOR SUITABLE LOCATIONS FOR A DRILLING REGIME AT AN UPSLOPE ROCKY KNOLL OF LAWU ESTATE, WESTERN BYPASS, MINNA, NIGERIA

Background: A client requested that the study group help determine locations that would be suitable for a drilling regime at his lot, located at an upslope rocky knoll of Lawu Estate, Minna, Nigeria. Aim: The aim of this study is to carry out a purpose-specific survey to pinpoint the best locations in a built-up property at the upmarket Lawu Estate that would be suitable for a drilling regime targeted for household consumption. Methods: The study area was reconnoitered by the survey crew in order to georeference the locations that would be occupied for the vertical electrical sounding survey in the 30 m x 20 m lot. Owing to the extensive build-up at this lot, only a four-point traverse along the 30-metric dimension traverse of the frontage of the building was demarcated in the northeasterly direction, thereby limiting the desire of the survey crew to define an appropriate survey grid. The data-acquisition pattern at the 4 x 1 survey stations of the frontage-traverse of the lot followed the “traditional” sequence of Schlumberger array layout measurements, whence the survey crew progressed with current-electrode spacing either end of a survey point located at this frontage-traverse targeting a maximum survey depth of 100 m. Result: The acquired vertical electrical-sounding data set for this study was recorded on purpose-specific data sheets. Discussion: Based on empirical rules-of-thumb procedures for interpreting vertical electrical sounding data at the Nigerian Basement Complex geological province, “assured” groundwater location and “strongly aquiferous” location, deductive inferences were drawn with regards to only vertical electrical sounding Station 4. Conclusion: Thus, it is recommended that VES Station 4 be exploited in the planned drilling program of the client, especially since this survey point checks off 100 percent of the constraints imposed by the rules-of-thumb interpretation procedures.
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RESEARCH LANDSCAPE OF REPURPOSED MEDICATIONS IN CANCER TREATMENT: A MULTI-DATABASE BIBLIOMETRIC ANALYSIS OF ELEVEN OFF-PATENT THERAPEUTICS

Background: Drug repurposing offers potential advantages for cancer therapy development, particularly when utilizing medications with established safety profiles and expired patents. While individual repurposed medications have been investigated for oncological applications, comprehensive comparative analyses of research distribution patterns across multiple therapeutic candidates appear limited in the literature. Understanding these patterns may provide insights into research priorities and potential knowledge gaps. Aim: This exploratory study was designed to quantify and compare the volume of scientific literature examining the anticancer potential of eleven selected off-patent medications across different pharmacological classes. Methods: Bibliometric searches were conducted across five databases (Google Scholar, BVS, PubMed, NIH, and Science.gov) using standardized search terms combining each medication name with "cancer" and "cancer treatment." The selected medications included ivermectin, fenbendazole, mebendazole, albendazole, metformin, propranolol, disulfiram, valproic acid, thalidomide, dexamethasone, and hydroxychloroquine. Basic statistical analyses were performed to examine the distribution patterns and correlations within the database. Results: The search yielded 3,226,066 total publications with considerable variation in distribution patterns. Dexamethasone accounted for the largest proportion (1,538,058 publications, 47.68%), followed by metformin (697,172 publications, 21.61%). Some medications with smaller overall publication volumes demonstrated higher proportions of treatment-specific research, such as fenbendazole (87.82%), disulfiram with copper (86.54%), and hydroxychloroquine with zinc (75.21%). The Herfindahl Index indicated a high concentration of research attention (0.2870). Discussion: The findings suggest substantial variation in research attention across the selected medications. While some medications dominate the literature, others with focused treatment-specific research may warrant further investigation. The inverse relationship observed between total publication volume and treatment specificity suggests that research patterns in this field may be more complex than absolute publication counts indicate. Conclusions: This preliminary bibliometric assessment reveals an uneven distribution of research attention among repurposed medications being investigated for cancer applications. These patterns may inform future research prioritization, though further qualitative analysis would be valuable to assess the clinical significance of these quantitative observations.
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General information

SOUTHERN JOURNAL OF SCIENCES

    General information about this journal
  • Title: SOUTHERN JOURNAL OF SCIENCES
  • Short Title: South. J. Sci.
  • ISSN: 2764-5959 (Online); ISSN: 2764-5967 (Print)
  • Universal Decimal Classification (UDC): 001
  • Review Process: Double-Blind Peer-Review
  • Accessibility: Platinum Open Access, NO-APCs.
  • Digital preservation: Portico
  • Frequency of Publication: biannual [2 issues per year]. Journal publication schedule
  • DOI: 10.48141/2764-5959
  • Website: https://www.sjofsciences.com/
  • Country: BRAZIL
  • Publisher: Araucária - Scientific Association.
  • Language of Publication: ENGLISH / PORTUGUESE*
  • *Year that the Journal started accepting manuscripts in Portuguese: 2020
  • First issue year: 1993
  • Free full text: Yes
  • Indexed in: Index Copernicus; Latindex, and I2OR.
  • Formerly known as the Southern Brazilian Journal of Chemistry (1993 to 2021).
  • Former ISSN: 2674-6891 (Online); Former ISSN: 0104-5431 (Print).
  • Website last update: 06/07/2025.

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PHYSICOCHEMICAL CHARACTERISTICS OF SUGARCANE JUICES SOLD AT THREE DIFFERENT POINTS IN CUIABÁ - MT

Background: Sugarcane juice is an excellent substrate for the growth of a large and diverse microbiota, and poor quality of it can affect the health of consumers. This study aimed to evaluate the acidity parameters of the juice extracted from minimally processed sugarcane at three different points in Cuiabá - MT. Methods: In the juice samples, the following parameters were analyzed: Brix (soluble solids), pH, acetic (volatile) acidity, and sulfuric (total) acidity. Results: All the Brix values were above 18. The pH values were between 5 and 6. The total and volatile acidity was below 0.8. Discussion: The Brix values found in this study are similar to other studies (standard deviation of 1.7). The variety of sugarcane significantly influences the Brix and its sampling period. Inappropriate handling of sugarcane promotes the microbiological decrease of the final product. The pH values were satisfactory, but the changes in temperature in one of the juices (sudden change from 24 to 22.7ºC) caused its pH to differ from the value found for the others. The total and volatile acidity content is related to the storage time of the juice, which can be contaminated by bacteria and microorganisms, affecting the characteristics of the product. When the acidity value is more significant than 0.8, there was a change in these characteristics, which did not happen in this work. Conclusions: The Brix values indicate an adequate maturation of the analyzed juices. The pH values are in the ideal range for sugarcane juice. The volatile and total acidity is in the ideal range, indicating quality standards for sugarcane juice.
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EVALUATION OF THE EFFECTIVENESS OF TREATMENT OF THE ORAL MUCOSA WITH PHYTO-OINTMENT BASED ON PHYTOECDYSTEROIDS

An indicator of the health of the human body in the state of the oral mucosa. Mechanical and chemical factors constantly influence it. At the first stage of the study, a comparative analysis of the frequency of various forms of traumatic injuries of the oral mucosa was carried out. The distribution of patients into groups was also carried out, depending on the medicinal product used. Then clinical examinations were carried out. After that, the therapy of traumatic erosive and ulcerative lesions of the oral mucosa began. The developed method for treating traumatic lesions of the oral mucosa with medicine based on phytoecdysteroids provides for eliminating the traumatic factor, applying ointment based on phytoecdysteroids to the dried out focus twice a day. The use of phyto-ointment leads to complete repair of traumatic erosive and ulcerative lesions of the oral mucosa on average by the eighth day from the start of treatment; a similar effect with the use of "Solcoseryl dental adhesive paste" is achieved by the tenth day, and the gel "Cholisal Dental" - at a later date, which is confirmed in this study. The most significant positive effect on the level of quality of life associated with the effectiveness of treatment of traumatic erosive and ulcerative lesions of the oral mucosa in comparison with the dental “Solcoseryl dental adhesive paste” and the gel “Cholisal Dental” is exerted by phyto-ointment, where a decrease in the total points was recorded. When conducting routine examinations of patients, it is necessary to pay attention to the oral mucosa damage. Moreover, in treating traumatic injuries of the oral mucosa, it is recommended to use phytoointment, which contains phytoecdysteroids.
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UTILIZATION OF PROTEOMICS APPROACH TO UNDERSTAND GENES ASSOCIATED WITH THE OCCURRENCE OF BIOTIC STRESS IN PLANTS

Of the most fundamental fields of modern biology is transcriptomics, with a focal point on the expression pattern of plants under various conditions by assessing ribonucleic acid. So far, this approach has been a game-changer in revealing the gene structure, function, and most importantly, their cellular and biological role. Considering the criticality of pathogens for crop plants, understanding plant defense mechanisms against them is in high demand. This study aimed to review the principles of these approaches and their recent application in the plant. An Important method to address this gap is transcriptomics, which can effectively provide insight into plants against pathogens. This field has covered different aspects of plant biology besides the plant-pathogen relationship. Identifying pathogens in infected plants and the series of reactions they provoke at the gene level is crucial to finding the responsible gene (s). Finding the gene associated with resistance or vulnerability to a specific pathogen paves the way to differentiate the potential genotypes. Thus, the breeding attempts would be more successful. The advancement in biotechnology has revolutionized this field with some of the methods that have been commonly applied in studies on the plant-pathogen relationship, for instance, Northern blotting, microarray, real-time polymerase chain reaction.
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SOUTHERN JOURNAL OF SCIENCES

The SOUTHERN JOURNAL OF SCIENCES publishes articles in Chemistry, Physics, Mathematics, Biology, Pharmacy, Medicine, Engineering, Industrial Science, Agriculture, and related interdisciplinary areas and is intended to fill a gap in terms of scientific information worldwide. All manuscripts can be published either in English or Portuguese, with tile, abstracts, and keywords in English. At present, there are NO PUBLICATION FEES. Editors will cover web hosting, open access, DOI number, and other service costs.

We have set high standards for the articles to be published by ensuring strong but fair refereeing by at least two reviewers. We hope that this Journal will provide a forum for disseminating high-quality research in chemistry and related areas and are open to any questions and suggestions. Starting in 2020, the SOUTHERN JOURNAL OF SCIENCES will have two issues per year (June and December).

Thank you very much for choosing the SOUTHERN JOURNAL OF SCIENCES to publish your paper!
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