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INTERVIEW WITH DEPUTY VICE CHANCELLOR DR. O. A. OMOTESHO, UNIVERSITY OF ILORIN, NIGERIA (ENGLISH VERSION)

Background: The University of Ilorin, founded in 1975 in Nigeria, has evolved from 3 to 16 faculties, becoming the country's most sought-after institution for the past two decades. Aims: To document the institutional evolution, identify the most demanded programs, assess scientific output, examine internationalization strategies, and understand strategic development objectives. Methods: Structured interview with Vice-Chancellor Dr. Olubumi Abayomi Omotesho, following a standardized protocol covering historical, academic, scientific, and strategic aspects of the institution, under Creative Commons license format. Results: The university expanded to 16 faculties in 49 years. The most demanded programs are Medicine and Nursing, followed by Pharmacy, Law, Engineering, and Accounting. Areas with the highest scientific output: Medicine, Biological/Agricultural Sciences, and Engineering. It offers 340 postgraduate programs with approximately 7,523 students. There is a dedicated infrastructure for internationalization, with plans for international accommodations. Discussion: The predominance of healthcare courses reflects global employability trends. Research aligned with Sustainable Development Goals demonstrates a contemporary vision. The institutional goal (number one in Nigeria, top 10 in Africa, top 500 globally) shows a measurable strategic approach. Commitment to internationalization aligns with global education trends. Conclusions: The institution exemplifies an evolving African university focused on academic excellence, scientific relevance, and internationalization. The prioritization of student-centered development, clear positioning goals, and international collaboration initiatives establish solid foundations for its contribution to regional and global knowledge.
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RESEARCH LANDSCAPE OF REPURPOSED MEDICATIONS IN CANCER TREATMENT: A MULTI-DATABASE BIBLIOMETRIC ANALYSIS OF ELEVEN OFF-PATENT THERAPEUTICS

Background: Drug repurposing offers potential advantages for cancer therapy development, particularly when utilizing medications with established safety profiles and expired patents. While individual repurposed medications have been investigated for oncological applications, comprehensive comparative analyses of research distribution patterns across multiple therapeutic candidates appear limited in the literature. Understanding these patterns may provide insights into research priorities and potential knowledge gaps. Aim: This exploratory study was designed to quantify and compare the volume of scientific literature examining the anticancer potential of eleven selected off-patent medications across different pharmacological classes. Methods: Bibliometric searches were conducted across five databases (Google Scholar, BVS, PubMed, NIH, and Science.gov) using standardized search terms combining each medication name with "cancer" and "cancer treatment." The selected medications included ivermectin, fenbendazole, mebendazole, albendazole, metformin, propranolol, disulfiram, valproic acid, thalidomide, dexamethasone, and hydroxychloroquine. Basic statistical analyses were performed to examine the distribution patterns and correlations within the database. Results: The search yielded 3,226,066 total publications with considerable variation in distribution patterns. Dexamethasone accounted for the largest proportion (1,538,058 publications, 47.68%), followed by metformin (697,172 publications, 21.61%). Some medications with smaller overall publication volumes demonstrated higher proportions of treatment-specific research, such as fenbendazole (87.82%), disulfiram with copper (86.54%), and hydroxychloroquine with zinc (75.21%). The Herfindahl Index indicated a high concentration of research attention (0.2870). Discussion: The findings suggest substantial variation in research attention across the selected medications. While some medications dominate the literature, others with focused treatment-specific research may warrant further investigation. The inverse relationship observed between total publication volume and treatment specificity suggests that research patterns in this field may be more complex than absolute publication counts indicate. Conclusions: This preliminary bibliometric assessment reveals an uneven distribution of research attention among repurposed medications being investigated for cancer applications. These patterns may inform future research prioritization, though further qualitative analysis would be valuable to assess the clinical significance of these quantitative observations.
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INQUIRY FOR SUITABLE LOCATIONS FOR A DRILLING REGIME AT AN UPSLOPE ROCKY KNOLL OF LAWU ESTATE, WESTERN BYPASS, MINNA, NIGERIA

Background: A client requested that the study group help determine locations that would be suitable for a drilling regime at his lot, located at an upslope rocky knoll of Lawu Estate, Minna, Nigeria. Aim: The aim of this study is to carry out a purpose-specific survey to pinpoint the best locations in a built-up property at the upmarket Lawu Estate that would be suitable for a drilling regime targeted for household consumption. Methods: The study area was reconnoitered by the survey crew in order to georeference the locations that would be occupied for the vertical electrical sounding survey in the 30 m x 20 m lot. Owing to the extensive build-up at this lot, only a four-point traverse along the 30-metric dimension traverse of the frontage of the building was demarcated in the northeasterly direction, thereby limiting the desire of the survey crew to define an appropriate survey grid. The data-acquisition pattern at the 4 x 1 survey stations of the frontage-traverse of the lot followed the “traditional” sequence of Schlumberger array layout measurements, whence the survey crew progressed with current-electrode spacing either end of a survey point located at this frontage-traverse targeting a maximum survey depth of 100 m. Result: The acquired vertical electrical-sounding data set for this study was recorded on purpose-specific data sheets. Discussion: Based on empirical rules-of-thumb procedures for interpreting vertical electrical sounding data at the Nigerian Basement Complex geological province, “assured” groundwater location and “strongly aquiferous” location, deductive inferences were drawn with regards to only vertical electrical sounding Station 4. Conclusion: Thus, it is recommended that VES Station 4 be exploited in the planned drilling program of the client, especially since this survey point checks off 100 percent of the constraints imposed by the rules-of-thumb interpretation procedures.
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General information

SOUTHERN JOURNAL OF SCIENCES

    General information about this journal
  • Title: SOUTHERN JOURNAL OF SCIENCES
  • Short Title: South. J. Sci.
  • ISSN: 2764-5959 (Online); ISSN: 2764-5967 (Print)
  • Universal Decimal Classification (UDC): 001
  • Review Process: Double-Blind Peer-Review
  • Accessibility: Platinum Open Access, NO-APCs.
  • Digital preservation: Portico
  • Frequency of Publication: biannual [2 issues per year]. Journal publication schedule
  • DOI: 10.48141/2764-5959
  • Website: https://www.sjofsciences.com/
  • Country: BRAZIL
  • Publisher: Araucária - Scientific Association.
  • Language of Publication: ENGLISH / PORTUGUESE*
  • *Year that the Journal started accepting manuscripts in Portuguese: 2020
  • First issue year: 1993
  • Free full text: Yes
  • Indexed in: Index Copernicus; Latindex, and I2OR.
  • Formerly known as the Southern Brazilian Journal of Chemistry (1993 to 2021).
  • Former ISSN: 2674-6891 (Online); Former ISSN: 0104-5431 (Print).
  • Website last update: 06/07/2025.

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CALCULATION FOR REDEMPTION OF COMPACT TESTING BY THE PROCTOR METHOD THROUGH NEWTON’S GRAVITATIONAL POTENTIAL ENERGY

Throughout this article, a study on the characteristics of the compaction test by the Proctor Method, regulated by ABNT NBR-7182, which is used to verify the degree of soil compaction, will be approached in order to broaden the discussion and raise points that demonstrate the urgent need to make it more accurate, efficient and safe. Through qualitative and quantitative research carried out by the authors of this article, it sought to collect data through a questionnaire for professionals in the field of geotechnics in the “Quadrilátero Ferrífero” region in Minas Gerais. In addition to other relevant data for the topic, it was raised that of the 22 professionals from the participating region, 72.7% of the total belief that the manual compaction test can be manipulated by an operator during the test execution, failing to generate results reliable, thus showing the importance of the proposed theme. In this way, we initially sought to correlate the Compaction Energy formula idealized by Ralph Proctor with Isaac Newton’s Gravitational Potential Energy formula and, through it, present the resizing, which may enable the construction of manual, semi-automatic human propulsion machines (not or making the automated ones that depend on electricity available to the market. In conclusion, from the mathematical calculations, it was possible to evidence the use of Newton’s Gravitational Potential Energy to constructnew equipment to carry out this test.
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COMPARATIVE STUDY OF DPD REAGENTS FOR CHLORINE MEASUREMENT IN DRINKING WATER AND DEVELOPMENT OF A JAVASCRIPT INTERPOLATION TOOL

Background: Determining chlorine in water ensures safety. Among other methods, the DPD colorimetric method is used. The DPD Method relies on colorimetric reactions to measure free and total chlorine concentration in water samples with pink compound formation. Aims: To perform a comparative chlorine analysis using DPD, assessing reagents from 3 makers and 2 Hach instruments to identify disparities and propose adjustments for more accurate measurements. Methods: Hach High-Range and Low-Range Free chlorine determination procedures were followed. DR300 and POCKET Colorimeter II spectrophotometers were used. Tests were conducted for each DPD manufacturer in low/high ranges and in two HACH devices to determine the chlorine concentrations. Hach was used as the reference; LaMotte and PoliControl compared against it. Statistical analyses were compiled using MS Excel. Results: The tests findings were gathered in Tables 1-5. JavaScript and HTML scripts were created to convert LaMotte and PoliControl outcomes into values equivalent to those of HACH through linear interpolation. Discussion: Various DPD reagents and equipment provided slightly different readings, prompting empirical evaluation of these differences. Adjusting the results to Hach's results was selected as both the reagent and spectrophotometer were from the same brand. Differences in spectrophotometer readings were more pronounced in high-range tests nearing the upper limit of the test. Conclusions: Equipment variations caused minor result differences; DPD reagents are not interchangeable without correlation. The Open-source code developed aided in reducing reading disparities.
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A COMPARATIVE STUDY ON THE RESPONSES OF TWO LINES OF SUGAR BEET (Beta vulgaris L) TO SALINITY

Sugar beet is a crop able to resist high levels of soil salinity after emergence and establishment. Considering the significant difference in the effect of nitrogen forms on sugar beet performance under normal conditions, the form of nitrogen may affect the performance of sugar beet plants under abiotic stress, particularly salinity. Additionally, exploring the most appropriate type of nitrogen for sugar beet could mean optimizing sucrose content. Therefore, here using two lines, sugar beet was grown in pots (filled with 4 kg soil), salt-resistance (line 7233- p.29 x Mst), and salt-sensitive (line 3929-21939), the effect of two different forms of nitrate in the form of calcium nitrate (1 g per pot) and ammonium in the form of ammonium sulfate (1 g per pot) under normal and salt stress condition (40 Millimoles per liter sodium chloride) were evaluated. The result revealed the positive influence of nitrate over ammonium by indicating higher dry weight in both sensitive line: 19.2 and 13.6 g, and tolerance line: 20.4 and 13.6 g, respectively alone and in combination with salinity stress. Similarly, root yield levels positively influenced by nitrate treatment either alone or under salinity stress (sensitive line: 194.5 and 243.2 g and tolerance line: 207 and 249.5 g). The outcomes additionally showed the accumulation of proline aerial parts in both lines, and however, the proline accumulation of sensitive line was higher (3.9 mg/g dry weight). Moreover, induction of proline aggregation was considerably higher in nitrate nitrogen-treated sensitive line (9.3 mg/g dry weight). The absence of significant difference was obseved between nitrogen treatments in terms of extractable sucrose and root molasses sugar. Also, the root impurities increased in those treated with nitrate-nitrogen and salinity. It can be concluded that nitrate-nitrogen has improved the performance of both sugar beet lines against salinity stress, and its practical application is adviseable.
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SOUTHERN JOURNAL OF SCIENCES

The SOUTHERN JOURNAL OF SCIENCES publishes articles in Chemistry, Physics, Mathematics, Biology, Pharmacy, Medicine, Engineering, Industrial Science, Agriculture, and related interdisciplinary areas and is intended to fill a gap in terms of scientific information worldwide. All manuscripts can be published either in English or Portuguese, with tile, abstracts, and keywords in English. At present, there are NO PUBLICATION FEES. Editors will cover web hosting, open access, DOI number, and other service costs.

We have set high standards for the articles to be published by ensuring strong but fair refereeing by at least two reviewers. We hope that this Journal will provide a forum for disseminating high-quality research in chemistry and related areas and are open to any questions and suggestions. Starting in 2020, the SOUTHERN JOURNAL OF SCIENCES will have two issues per year (June and December).

Thank you very much for choosing the SOUTHERN JOURNAL OF SCIENCES to publish your paper!
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