D-DIMER A RISK FACTOR ASSOCIATED WITH C-REACTIVE PROTEIN FOR PREDICTING THE SEVERITY OF INFECTION BY COVID-19
Background: COVID-19, caused by SARS-CoV-2, has unresolved mortality risk factors and clinical course, highlighting the need for further research. Aims: The study aimed to asses D-dimer and C-Reactive Protein (CRP) as the risk factors for severity covid-19 and who are less capable of surviving. Methods: A retrospective study conduct of COVID-19 in adult inpatients aged >20 at Al-sadder and Alamal Hospital in Iraq. Demographics, clinical trials, treatments, and viral RNA samples were analyzed. The study involved 100 patients, with 67 discharged and 33 hospitalized died. The majority of the participants 45% were aged < 40, but 55% were aged >40 years. Results: A significant and 57% were male 37(55.2%) Survivor vs. 20 (60.6%) non-survivor, p=0.024), more than 43% were female (30(44.8%) Survivor vs. 13(39.4%) non-survivor, p=0.010. Patients had underlying comorbidities (66%), survivor 37(55%), and non-survivor 29(87%). The most prominent comorbidity in non-survivors more than survivors was diabetic mellitus 85%, asthma 58%, stroke 48%, renal failure 42%, heart strake 33%, and hypertension 18%. The study found significant differences in WBC, lymphocyte count, D-dimer, Ferritin, CRP, and LDH levels in non-survivors compared to survivor patients, with a positive correlation between D- dimer and these parameters. The ROC analysis curve showed CRP with a high AUC of 80.2%, 87.9% sensitivity, and 37.3% specificity, while D-dimer and LDH had AUCs of 0.74.9 and 70%, respectively. Discussion: The study found that older age, higher d-dimer, ferritin, CRP, and LDH are associated with disease severity and higher mortality risk in adult COVID-19 patients. Conclusions: These biomarkers could aid in early detection of disease progression signs and better patient management
Read ArticleMANAGEMENT MODEL FOR CONSTRUCTION WASTE PRODUCED IN THE CITY OF RIO DE JANEIRO
Background: A new management model for construction and demolition waste (CDW) was proposed for the city of Rio de Janeiro, hence waste the city planning area estimated generation; the results were compared with the data published by COMLURB and SNIS through the statistics tests was proved that CDW had been dispersed, which support the hypothesis that the current model cause dispersion of the rubble. Aim: This study proposes a new management model for CDW to the city, according to regions where occur the higher production of rubble. Methods: The estimation of rubble was obtained through the issued licenses from 2006 to 2020 published by SMPU. The quantification of rubble in the city was carried out by adopting the generation indicator from licensed construction activities. The amount of CDW published by COMLURB and SNIS was compared through statistics tests ANOVA and T-Test, the second period from 2006 to 2020 and 2011 to 2020. To measure the area to implant a CDW recycling plant, criteria from production capacity were used. Results: ANOVA test to data from 2006 to 2020 and 2011 to 2020, according to a confidence interval of 95%, found the P value 0.589 and 0.022, respectively, it was verified that the significant difference is between data from COMLURB and Estimated. The T-test was applied from the same period in data from SNIS and estimated the P values 0.399 and 0.014. Discussion: The data from Estimating between 2006 and 2020 showed the best representation. The Área de Planejamento – AP (Planning Area) 4 was where 50.70% of the total rubble, after the AP 3 with 17.66%, the AP 5 was estimated at 16.59%, last of all, AP 2 and AP 1 were calculated the generation of 8.28% and 6.77%, respectively. Therefore, sizing the CDW recycling producing 361,99.00 tons per year demands an area of 32,397.50 m². Conclusions: It was concluded that the receipt of CDW in transfer stations managed by COMLURB is not allowed; therefore, the need to create a construction waste recycling plant was presented, to this end, it is necessary to have an available area of approximately 32,397.50 m².
Read ArticleINDICATORS OF TRYPSIN-LIKE ACTIVITY OF MIXED SALIVAAFTER INSTALLING THE ENDOSSEOUS IMPLANTS IN THE PRESENCE OF GASTRIC ULCER AND DUODENAL ULCER
The trypsin-like activity of mixed saliva in orthopedic patients after implant placement was monitored. Proved negative impact on the processes of repair of background somatic pathology (peptic ulcers and 12 duodenal ulcers), justify the application of immunomodulator "Erbisol" as a drug that speeds up the repair processes during implantation. At present, the relevant issues are those related to the development of inflammatory complications at the stage of rehabilitation of patients, especially in the presence of somatic pathology and the study of the tissue complex of the implantation zone. Peptic ulcer disease occupies one of the main places in the structure of lesions of the digestive system. The close interdependence between the pathology of internal organs and the oral cavity is confirmed by numerous observations and studies.Implant placement is accompanied by changes in the enzymatic activity of mixed saliva. The presence of somatic pathology (ulcerative disease of the stomach and 12 duodenal ulcers) often leads to more long-term violations of the enzymatic activity of saliva. The use of the drug "Erbisol" in orthopedic dentistry accelerates the repair process, as evidenced by the earlier periods of normalization of the enzymatic activity of mixed saliva, after the installation of implants.Regular and timely monitoring of the condition of the periarticular tissues, as well as objective diagnosis of early inflammatory complications, are necessary to ensure the reliability and long-term functioning of prosthetic structures installed on implants in the oral cavity.It can be concluded that the purpose of our study was to study the trypsin-like activity (TPA) of mixed saliva after implant placement on the background of somatic pathology.
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