SOUTHERN JOURNAL OF SCIENCES

Background: Candidiasis, caused mainly by Candida albicans yeast, is a pathology that affects a significant amount of people in the world, mainly women, thus being a public health issue. In addition, clinical practice has found it difficult to treat candidiasis for two reasons: the multidrug resistance associated with the exacerbated use of available drugs and the high number of side effects caused by current antifungal drugs. In this scenario, this work is a literature review on the antifungal activity of metal complexes against C. albicans since they are extensively studied for their varied applications in health sciences, as an object of study in the area of inorganic chemistry, in the subareas of bioinorganic chemistry and pharmaceutical chemistry. Aim: The present work consists of a literature review in electronic databases on the potential antifungal action against Candida albicans presented by metal complexes. Methods: Data was collected using the Capes, PubMed, Cochrane Reviews and Virtual Health Library (BVS) databases. Results: The results obtained through bibliographic surveys show the importance of studies of metal complexes against the strain of C. albicans, which have promising inhibitory activities and in some cases, with Minimum Inhibitory Concentration (MIC) values lower than 20µg/mL Discussion: The results obtained through bibliographic surveys show the importance of studies of metal complexes against the strain of C. albicans, which have promising inhibitory activities, and in some cases, with Minimum Inhibitory Concentration (MIC) values lower than 20µg/mL. Conclusion: Highlighting the activity performed by ruthenium complexes and Schiff bases when coordinated to metallic ions arouses great interest in a future study of a complex of this metal with a Schiff base in its coordination site.

Background: The interview with Professor José de Ribamar, conducted by Luís de Boni, addresses various aspects of his career and contributions to chemistry in Brazil. The conversation includes his experiences in teaching, research, and university administration, as well as his role as President of the Federal Council of Chemistry (CFQ). Aims: The primary aim of the interview is to highlight Professor Ribamar's achievements and challenges throughout his career, and to explore his views on chemistry and its impact on scientific and educational development in Brazil. Methods: The interview was conducted in a question-and-answer format, allowing Professor Ribamar to share his experiences and insights in a detailed and personal manner. The interview was recorded, transcribed, and is available in both text and video formats. Results: Professor Ribamar detailed his academic and professional journey, including his undergraduate and graduate studies in chemistry, his contributions as a professor at the Federal University of Maranhão (UFMA), and his initiatives as a course coordinator and department head. He also discussed the impact of his research and his vision for the future of chemistry, emphasizing the importance of artificial intelligence and algorithms in predicting chemical models. Discussion: The interview provided a comprehensive overview of Professor Ribamar's contributions to chemistry in Brazil. He emphasized the importance of education and ongoing research for scientific advancement, as well as the need to adapt to new technologies. The discussion also addressed the challenges the scientific community faces and the importance of interdisciplinary collaboration. Conclusion: Professor José Ribamar has significantly promoted and developed chemistry in Brazil in academia and public administration. His career illustrates the importance of dedication to education and research, and his reflections offer valuable lessons for future generations of scientists and educators. The interview serves as a testament to his lasting impact on the scientific community.

Throughout this article, a study on the characteristics of the compaction test by the Proctor Method, regulated by ABNT NBR-7182, which is used to verify the degree of soil compaction, will be approached in order to broaden the discussion and raise points that demonstrate the urgent need to make it more accurate, efficient and safe. Through qualitative and quantitative research carried out by the authors of this article, it sought to collect data through a questionnaire for professionals in the field of geotechnics in the “Quadrilátero Ferrífero” region in Minas Gerais. In addition to other relevant data for the topic, it was raised that of the 22 professionals from the participating region, 72.7% of the total belief that the manual compaction test can be manipulated by an operator during the test execution, failing to generate results reliable, thus showing the importance of the proposed theme. In this way, we initially sought to correlate the Compaction Energy formula idealized by Ralph Proctor with Isaac Newton’s Gravitational Potential Energy formula and, through it, present the resizing, which may enable the construction of manual, semi-automatic human propulsion machines (not or making the automated ones that depend on electricity available to the market. In conclusion, from the mathematical calculations, it was possible to evidence the use of Newton’s Gravitational Potential Energy to constructnew equipment to carry out this test.